| Identification | More | [Name]
4-Methylsulfonylaniline | [CAS]
5470-49-5 | [Synonyms]
4-mesylaniline
4-(METHYLSULFONYL)ANILINE
4-METHYLSULFONYL-BENZENEAMINE
4-(METHYLSULPHONYL)ANILINE
BENZENEAMINE, 4-METHYLSULFONYL-
-(Methylsulfonyl)aniline
Benzenamine, 4-(methylsulfonyl)-
niline, p-(methylsulfonyl)-
4-AMINOPHENYL METHYL SULFONE
4-MethylsulfonylanilineHCl
4-METHYLSULPHONYLANILINE HYDROCHLORIDE 95%
4-Methyl-Sulphony aniline
4-(methylsulfonyl)phenylamine
p-(Methylsulfonyl)aniline
4-(Methylsulfonyl)benzenamine | [EINECS(EC#)]
226-803-8 | [Molecular Formula]
C7H9NO2S | [MDL Number]
MFCD00025353 | [Molecular Weight]
171.22 | [MOL File]
5470-49-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
243-245°C | [Boiling point ]
384.3±34.0 °C(Predicted) | [density ]
1.44 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated) | [form ]
Crystalline Powder | [pka]
pK1:1.48(+1) (25°C) | [color ]
White | [Water Solubility ]
Soluble in water. | [Sensitive ]
Light Sensitive | [InChI]
1S/C7H9NO2S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H,8H2,1H3 | [InChIKey]
XJEVFFNOMKXBLU-UHFFFAOYSA-N | [SMILES]
CS(=O)(=O)c1ccc(N)cc1 | [CAS DataBase Reference]
5470-49-5(CAS DataBase Reference) | [NIST Chemistry Reference]
4-Aminophenyl methyl sufhone(5470-49-5) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
WGK 3 | [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [HS Code ]
2930909899 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
It is used as pharmaceutical intermediate. A series of 4-(methylsulfonyl)aniline derivatives were synthesized in order to obtain new compounds as a potential anti-inflammatory agents with expected selectivity against COX-2 enzyme. | [Synthesis Reference(s)]
Tetrahedron Letters, 35, p. 7867, 1994 DOI: 10.1016/0040-4039(94)80139-8 |
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