| Identification | Back Directory | [Name]
DROFENINE HYDROCHLORIDE | [CAS]
548-66-3 | [Synonyms]
it-19
trasentinh
DrofeninHCl
DROFENINE HCL
cyclovegantine
cycloadiphenine
hexahydroadiphenine
Drofeninhydrochlorid
LABOTEST-BB LT00244841
DROFENINE HYDROCHLORIDE
cyclospasmol(tempelhof)
adipheninehhydrochloride
trasentine-6hhydrochloride
cycloadipheninehydrochloride
HEXAHYDROADIPHENINE HYDROCHLORIDE
2-(diethylamino)ethylalpha-cyclohexylbenzeneacetate
cyclohexylphenylacetyldiethylaminoethanolhydrochloride
2-(2-cyclohexyl-2-phenylacetoxy)ethyldiethylammonium chloride
2-diethylaminoethyl alpha-cyclohexylphenylacetate hydrochloride
2-diethylaminoethyl(alpha-phenylcyclohexane)acetatehydrochloride
alpha-cyclohexylbenzeneaceticacid2-(diethylamino)ethylesterhydrochloride
alpha-phenylcyclohexaneaceticacid2-(diethylamino)ethylesterhydrochloride
alpha-phenyl-cyclohexylessigsaeure-2-diaethylamino-aethylester-hydrochlorid | [EINECS(EC#)]
208-954-1 | [Molecular Formula]
C20H32ClNO2 | [MDL Number]
MFCD00034983 | [MOL File]
548-66-3.mol | [Molecular Weight]
353.93 |
| Chemical Properties | Back Directory | [Melting point ]
145-147° | [storage temp. ]
2-8°C
| [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Originator]
Trasentine A,Ciba | [Uses]
Spasmolytic | [Manufacturing Process]
17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in
200 parts of acetic acid and hydrogenated over platinum catalyst. After the
calculated volume of hydrogen was passed, the catalyst was filtered off and
the solvent was removed to dryness. Ether, water and a potassium carbonate
solution were added to the remaining oil and were thoroughly shaken. The
ether layer was washed with water and dried over potassium carbonate. The
solvent was removed, the remaining oil was distilled in vacuum to give 2-
(diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride. | [Therapeutic Function]
Spasmolytic | [IC 50]
BChE | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
AFINE CHEMICALS LIMITED
|
| Telephone: |
+86-571-85134551 +86-18958018566 |
| Website: |
www.afinechem.com/index.html |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-29-87569266 +86-17392581500 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-220/ |
|