ChemicalBook--->CAS DataBase List--->549-84-8

549-84-8

549-84-8 Structure

549-84-8 Structure
IdentificationBack Directory
[Name]

methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate
[CAS]

549-84-8
[Synonyms]

Amsonin
Amsonine
β-Yohimbine
beta-Yohimbine
Methyl (16?,17?)-17-hydroxyyohimban-16-carboxylate
methyl (16alpha,17beta)-17-hydroxyyohimban-16-carboxylate
Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16a,17b)-
2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester
[EINECS(EC#)]

208-977-7
[Molecular Formula]

C21H26N2O3
[MDL Number]

MFCD01741368
[MOL File]

549-84-8.mol
[Molecular Weight]

354.44
Hazard InformationBack Directory
[Uses]

β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A)-resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL)[1].
[References]

[1] dos Santos Torres ZE, et al. Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids. Molecules. 2013 May 29;18(6):6281-97. DOI:10.3390/molecules18066281
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