| Identification | Back Directory | [Name]
1-PHENYLBIGUANIDE HYDROCHLORIDE | [CAS]
55-57-2 | [Synonyms]
Compound PDK0269
PHENYL BIGUANIDE HCL
1-PhenylbiguanideHCl
PHENYL BIGUANIDE HYDROCHLORIDE
1-PHENYLBIGUANIDE HYDROCHLORIDE
phenylbiguanidemonohydrochloride
1-phenyl-biguanidmonohydrochloride
n’-phenylbiguanidemonohydrochloride
1-PHENYLBIGUANIDE MONOHYDROCHLORIDE
1-Phenylbiguanide hydrochloride 98%
N-PhenyliMidodicarboniMidic diaMide hydrochloride
n-phenyl-imidodicarbonimidicdiamidmonohydrochloride
n-phenyl-imidodicarbonimidicdiamidemonohydrochloride
1-(diaminomethylidene)-2-phenylguanidine,hydrochloride
1-carbamimidamido-N-phenylmethanimidamide hydrochloride | [EINECS(EC#)]
200-239-2 | [Molecular Formula]
C8H12ClN5 | [MDL Number]
MFCD00035040 | [MOL File]
55-57-2.mol | [Molecular Weight]
213.67 |
| Chemical Properties | Back Directory | [Melting point ]
244-247 °C(lit.) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly, Sonicated), Water (Slightly, Sonicated) | [form ]
Solid | [color ]
Prisms | [Stability:]
Hygroscopic | [InChI]
1S/C8H11N5.ClH/c9-7(10)13-8(11)12-6-4-2-1-3-5-6;/h1-5H,(H6,9,10,11,12,13);1H | [InChIKey]
FHUDRDSKZQDCBC-UHFFFAOYSA-N | [SMILES]
Cl.NC(=N)NC(=N)Nc1ccccc1 | [EPA Substance Registry System]
Imidodicarbonimidic diamide, N-phenyl-, monohydrochloride (55-57-2) |
| Safety Data | Back Directory | [WGK Germany ]
3 | [RTECS ]
DU2550000 | [TSCA ]
TSCA listed | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral | [Toxicity]
LD50 orl-mus: 1200 mg/kg CKFRAY1,434,52 |
| Hazard Information | Back Directory | [Uses]
1-Phenylbiguanide Hydrochloride is a SR-3 agonist. Possesses cardiovascular effects in anesthetized dogs. | [Safety Profile]
Poison by intraperitoneal route. Moderately toxic by ingestion.When heated to decomposition it emits very toxic fumes of HCl and NOx. | [in vivo]
In anaesthetised mice, Phenylbiguanide (PBG), a drug that is known to stimulate cardiopulmonary afferent C-fibres,is injected into the right atrium of the heart and mapped c-Fos expression within specific regions of the central nervous system. Intraatrial injection of PBG produces a reflex cardiorespiratory response including a pronounced bradycardia and a respiratory depression[3]. | [IC 50]
5-HT3 Receptor: 3 μM (EC50) | [storage]
Room temperature |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|