| Identification | Back Directory | [Name]
7-METHYL-6-THIOGUANOSINE | [CAS]
55727-10-1 | [Synonyms]
MESG
7-METHYL-6-THIOGUANOSINE
7-Methyl-6-thio-D-guanosine
6-mercapto-7-methylguanosine
7-Methyl-6-thioguanosine inner salt
7-methyl-6-Thioguanosine (technical grade)
2-AMino-6-Mercapto-7-Methylpurine Ribonucleoside
MESG [2-AMino-6-Mercapto-7-Methylpurine, inner salt]
2-AMino-6-Mercapto-7-Methyl-9-β-D-ribofuranosylpuriniuM Hydroxide, Inner Salt | [Molecular Formula]
C11H15N5O4S | [MDL Number]
MFCD01631009 | [MOL File]
55727-10-1.mol | [Molecular Weight]
313.33 |
| Chemical Properties | Back Directory | [Melting point ]
>175°C (dec.) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMF: 50 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [color ]
White to yellow | [Stability:]
Air sensitive, Light sensitive, Temperature sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Solid | [Uses]
7-Methyl-6-thioguanosine (MESG) is a chromophoric substrate which can be used for the quantitation of inorganic phosphate. 7-Methyl-6-thioguanosine is also used to determine the activity of purine nucleoside phosphorylase[1][2]. | [References]
[1] Cheng Q, et al. A continuous spectrophotometric assay for protein phosphatases. Anal Biochem. 1995 Mar 20;226(1):68-73. DOI:10.1006/abio.1995.1192
[2] Anna-Maja Aberg, et al. Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Scand J Clin Lab Invest. 2010 Feb;70(1):8-14. DOI:10.3109/00365510903359229 |
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