| Identification | Back Directory | [Name]
IsobavachroMene | [CAS]
56083-03-5 | [Synonyms]
IsobavachroMene
4-Hydroxylonchocarpin
4-Hydroxylonchocarpin/Isobavachromene
(2E)-1-(5-Hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one,1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-,(E)-
2-Propen-1-one, 1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-, (2E)- | [Molecular Formula]
C20H18O4 | [MDL Number]
MFCD21333543 | [MOL File]
56083-03-5.mol | [Molecular Weight]
322.35 |
| Chemical Properties | Back Directory | [Melting point ]
203-204℃ | [Boiling point ]
535.1±50.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
7.25±0.40(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
4-Hydroxylonchocarpin is a chalcone compound from an extract of Psoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities[1]. | [References]
[1] Lim J, et al. Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase. Exp Dermatol. 2016 Jul;25(7):574-6. DOI:10.1111/exd.13004 |
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