56377-67-4

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56377-67-4 Structure

Identification	Back Directory
[Name] tirotundin
[CAS] 56377-67-4
[Synonyms] NSC 249959 tirotundin Tagitinin D Tirotundine 2-Methylpropanoic acid (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester Propanoic acid, 2-methyl-, (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester
[Molecular Formula] C19H28O6
[MDL Number] MFCD20275050
[MOL File] 56377-67-4.mol
[Molecular Weight] 352.42

Hazard Information	Back Directory
[Uses] Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1].
[References] [1] Rüngeler P, et al. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets. Planta Med. 1998 Oct;64(7):588-93. DOI:10.1055/s-2006-957527

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