| Identification | Back Directory | [Name]
[S,(+)]-3,4-Dihydro-4,9-dihydroxy-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione | [Synonyms]
4,9-Dihydroxy-α-lapachone
(+)-4,9-Dihydroxy-α-lapachone
4,9-Dihydroxy-alpha-lapachone
[S,(+)]-3,4-Dihydro-4,9-dihydroxy-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione
2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-4,9-dihydroxy-2,2-dimethyl-, (4S)- | [MDL Number]
MFCD20261016 | [Molecular Weight]
274.27 |
| Chemical Properties | Back Directory | [Boiling point ]
495.3±45.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
6.86±0.60(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Description]
4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells.
4,9-Dihydroxy-alpha-lapachone exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC(50) value of 73 microM. | [Uses]
Catalpanp-1 is a potent anti-microbial agent. Catalpanp-1 has strong antimicrobial effect on yeast, bacteria, fungi and the like[1]. | [target]
NO | [References]
[1] Composition for inhibiting growth of microorganisms containing catalpanp-1 with structure of 4,9-dihydroxy-2,2-dimethyl-3,4-dihydronaphtho[2,3-b]pyran-5,10-dione. Patent, KR2004019805 A. 2002-08-30. |
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| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
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