566-14-3

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566-14-3 Structure

Identification	Back Directory
[Name] EUPHORBOL
[CAS] 566-14-3
[Synonyms] EUPHORBOL Euphorbadienol alpha-Euphorbol (13α,14β,17α,20S)-24-Methylene-5α-lanost-8-en-3β-ol Lanost-8-en-3-ol, 24-methylene-, (3β,13α,14β,17α,20S)-
[Molecular Formula] C31H52O
[MDL Number] MFCD07785160
[MOL File] 566-14-3.mol
[Molecular Weight] 440.74

Chemical Properties	Back Directory
[storage temp. ] 2-8°C
[form ] solid
[InChI] 1S/C31H52O/c1-20(2)21(3)10-11-22(4)23-14-18-31(9)25-12-13-26-28(5,6)27(32)16-17-29(26,7)24(25)15-19-30(23,31)8/h20,22-23,26-27,32H,3,10-19H2,1-2,4-9H3
[InChIKey] XJLZCPIILZRCPS-UHFFFAOYSA-N
[SMILES] OC1C(C2C(CC1)(C3=C(C4(C(C(CC4)C(CCC(=C)C(C)C)C)(CC3)C)C)CC2)C)(C)C

Safety Data	Back Directory
[WGK Germany ] WGK 3
[Storage Class] 11 - Combustible Solids

Hazard Information	Back Directory
[Uses] Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity[1][2].
[IC 50] Trypanosoma; Leishmania
[References] [1] Smaili A, et al. Triterpene derivatives from Euphorbia enhance resistance against Verticillium wilt of tomato. Phytochemistry. 2017 Mar;135:169-180. DOI:10.1016/j.phytochem.2016.12.017 [2] Mazoir N, et al. Antileishmanial and antitrypanosomal activity of triterpene derivatives from latex of two Euphorbia species. Z Naturforsch C J Biosci. 2011 Jul-Aug;66(7-8):360-6. DOI:10.1515/znc-2011-7-807

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