| Identification | Back Directory | [Name]
EUPHORBOL | [CAS]
566-14-3 | [Synonyms]
EUPHORBOL
Euphorbadienol
alpha-Euphorbol
(13α,14β,17α,20S)-24-Methylene-5α-lanost-8-en-3β-ol
Lanost-8-en-3-ol, 24-methylene-, (3β,13α,14β,17α,20S)- | [Molecular Formula]
C31H52O | [MDL Number]
MFCD07785160 | [MOL File]
566-14-3.mol | [Molecular Weight]
440.74 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
solid | [InChI]
1S/C31H52O/c1-20(2)21(3)10-11-22(4)23-14-18-31(9)25-12-13-26-28(5,6)27(32)16-17-29(26,7)24(25)15-19-30(23,31)8/h20,22-23,26-27,32H,3,10-19H2,1-2,4-9H3 | [InChIKey]
XJLZCPIILZRCPS-UHFFFAOYSA-N | [SMILES]
OC1C(C2C(CC1)(C3=C(C4(C(C(CC4)C(CCC(=C)C(C)C)C)(CC3)C)C)CC2)C)(C)C |
| Hazard Information | Back Directory | [Uses]
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity[1][2]. | [IC 50]
Trypanosoma; Leishmania | [References]
[1] Smaili A, et al. Triterpene derivatives from Euphorbia enhance resistance against Verticillium wilt of tomato. Phytochemistry. 2017 Mar;135:169-180. DOI:10.1016/j.phytochem.2016.12.017
[2] Mazoir N, et al. Antileishmanial and antitrypanosomal activity of triterpene derivatives from latex of two Euphorbia species. Z Naturforsch C J Biosci. 2011 Jul-Aug;66(7-8):360-6. DOI:10.1515/znc-2011-7-807 |
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Merck KGaA
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