| Identification | Back Directory | [Name]
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN | [CAS]
56701-24-7 | [Synonyms]
VESTITOL
(+/-)-Vestitol
VESTITOL(RG)(PLEASE CALL)
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
3-(2-Hydroxy-4-methoxyphenyl)-7-chromanol
3-(2-Hydroxy-4-methoxyphenyl)chroman-7-ol
3-（2-Hydroxy-4-Methoxyphenyl）-3,4-Dihydro-2H-Chromen-7-Ol
3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
3-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)- | [Molecular Formula]
C16H16O4 | [MDL Number]
MFCD00075893 | [MOL File]
56701-24-7.mol | [Molecular Weight]
272.3 |
| Chemical Properties | Back Directory | [Melting point ]
172-179℃ | [Boiling point ]
418.5±45.0 °C(Predicted) | [density ]
1.282±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
9.53±0.40(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
Vestitol is the compound isolated from leaves of Trifolium arvense[1]. | [Definition]
ChEBI: Vestitol is a member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. It has a role as an anti-inflammatory agent, a plant metabolite and a phytoalexin. It is an aromatic ether, a member of hydroxyisoflavans and a methoxyisoflavan. | [Biological Activity]
Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities.
(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolislicorice root and other sources th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml). | [References]
[1] John L. Ingham, et al. Notizen: Isoflavonoid Phytoalexins from Leaves of Trifolium arvense. |
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