| Identification | Back Directory | [Name]
3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride | [CAS]
5688-80-2 | [Synonyms]
GOAXEHDWLMGWIV-UHFFFAOYSA-N
(±)-3,4,5-Trimethoxyamphetamine hydrochloride (TMA)
3,4,5-Trimethoxy-α-methylbenzeneethanamine hydrochloride
3,4,5-Trimethoxyamphetamine (hydrochloride) (exempt preparation) | [Molecular Formula]
C12H20ClNO3 | [MOL File]
5688-80-2.mol | [Molecular Weight]
261.745 |
| Hazard Information | Back Directory | [Description]
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50 = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications. | [Uses]
3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50s = 5.15 and 5.31 for phosphatidyl inositol release through 5-HT2A and 5-HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical] | [References]
[1] ARIANE WOHLFARTH Sebastian D Wolfgang Weinmann. LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum[J]. Analytical and Bioanalytical Chemistry, 2010, 396 7: 2403-2414. DOI: 10.1007/s00216-009-3394-4
[2] PABLO R MOYA. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors.[J]. Journal of Pharmacology and Experimental Therapeutics, 2007, 321 3: 1054-1061. DOI: 10.1124/jpet.106.117507 |
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