| Identification | Back Directory | [Name]
2-ThiazolaMine, 4-(4-chloro-2-thienyl)- | [CAS]
570407-10-2 | [Synonyms]
Avatrombopag Impurity 8
4-(4-Chloro-2-thienyl)-2-thiazolamine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)-
4-(4-Chlorothiophen-2-yl)thiazol-2-amine
2-Amino-4-(4-chlorothiophen-2-yl)thiazole
4-(4-chlorothiophen-2-yl)-1,3-thiazol-2-amine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine, 4-(4-chloro-2-thienyl)- | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C7H5ClN2S2 | [MDL Number]
MFCD24627156 | [MOL File]
570407-10-2.mol | [Molecular Weight]
216.711 |
| Chemical Properties | Back Directory | [Boiling point ]
395.3±27.0 °C(Predicted) | [density ]
1.535±0.06 g/cm3(Predicted) | [pka]
3.47±0.10(Predicted) | [InChI]
InChI=1S/C7H5ClN2S2/c8-4-1-6(11-2-4)5-3-12-7(9)10-5/h1-3H,(H2,9,10) | [InChIKey]
SMBPGSKGPGBYBQ-UHFFFAOYSA-N | [SMILES]
S1C=C(C2SC=C(Cl)C=2)N=C1N |
| Hazard Information | Back Directory | [Uses]
4-(4-Chloro-2-thienyl)-2-thiazolamine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | [Synthesis]
Bromine was added to an ether solution of 4-chloro-2-acetylthiophene under ice cooling, and the mixture was stirred at room temperature for 2 hours to obtain a brominated compound. Thiourea was added to an EtOH solution of the brominated compound at room temperature, and the mixture was stirred overnight at 80??C to obtain 2-amino-4-(4-chlorothiophen-2-yl)thiazole. |
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