| Identification | Back Directory | [Name]
POMIFERIN | [CAS]
572-03-2 | [Synonyms]
Pomiferin (NSC 5113)
3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
3-(3,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 3-(3,4-dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C25H24O6 | [MDL Number]
MFCD00075996 | [MOL File]
572-03-2.mol | [Molecular Weight]
420.45 |
| Chemical Properties | Back Directory | [Melting point ]
>300℃ | [Boiling point ]
673.5±55.0 °C(Predicted) | [density ]
1.314±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
6.85±0.40(Predicted) | [color ]
Light yellow to yellow | [biological source]
plant |
| Hazard Information | Back Directory | [Definition]
ChEBI: Pomiferin is a member of isoflavanones. | [Biological Activity]
Pomiferin acts as an potential inhibitor of HDACwith an IC50 of 1.05 μMand also potently inhibits mTOR (IC506.2 μM). Pomiferin shows cytotoxic effects on human tumor cell lines. Pomiferin also increases SOD activities and total antioxidative capacityand decreases malondialdehyde in rats. | [in vivo]
Pomiferin (5, 10 and 20 mg/kg, p.o.) shows protective effects on the treatment of reperfusion injury. Pomiferin also increases SOD activities and total antioxidative capacity, and decreases malondialdehyde in rats[3]. | [IC 50]
HDAC: 1.05 μM (IC50); mTOR: 6.2 μM (IC50) |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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