| Identification | Back Directory | [Name]
3,3',4',5,6,7,8-heptamethoxyflavone | [CAS]
1178-24-1 | [Synonyms]
NSC 618928
3-Methoxynobiletin
5,6,7,8,3,4-hepteMthoxyflavone
3,5,6,7,8,3',4'-hepteMthoxyflavone
3',4',3,5,6,7,8-Heptamethoxyflavone
2-(3,4-Dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,6,7,8-pentamethoxy- | [Molecular Formula]
C22H24O9 | [MDL Number]
MFCD00210513 | [MOL File]
1178-24-1.mol | [Molecular Weight]
432.42 |
| Chemical Properties | Back Directory | [Melting point ]
129-131 °C | [Boiling point ]
618.7±55.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [solubility ]
DMSO: soluble; Methanol: soluble | [form ]
A solid |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Citrus aurantium. | [Uses]
Used for content determination/identification/pharmacological experiments, etc. | [Definition]
ChEBI: 3-Methoxynobiletin is a member of flavonoids and an ether. | [Biological Activity]
3,5,6,7,8,3',4'-Heptemthoxyflavone is a flavonoid in mandarin orange peel with anti-tumor initiating and anti-neuroinflammatory activities. 3,5,6,7,8,3',4'-Heptemthoxyflavone inhibits collagenase activity and increases the content of type I procollagen in human dermal fibroblast neonatal (HDFn) cells. 3,5,6,7,8,3',4'-Heptemthoxyflavone induces brain-derived neurotrophic factor (BDNF) expression via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells. |
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