| Identification | More | [Name]
4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID | [CAS]
5731-10-2 | [Synonyms]
4FC
STK034344
4PND-Q05-0
AKOS B025021
AKOS BAR-0028
651710_ALDRICH
RARECHEM AL BE 1240
CHEMBRDG-BB 4400446
ART-CHEM-BB B025021
4-(4-FLUOROPHENYL)BENZOIC ACID
4'-fluorobiphenyl-4-carboxylate
4'-Fluoro-4-biphenylcarboxylic acid
4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID
4-BIPHENYL-4'-FLUORO-CARBOXYLIC ACID
4-Biphenyl-4'-fluoro-carboxylicacid
4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
[1,1'-BIPHENYL]-4-CARBOXYLIC ACID, 4'-FLUORO-
4'-fluorobiphenyl-4-carboxylic acid(SALTDATA: FREE)
4-(4-Fluorophenyl)benzoic acid, 4-Carboxy-4'-fluorobiphenyl | [Molecular Formula]
C13H9FO2 | [MDL Number]
MFCD01631909 | [Molecular Weight]
216.21 | [MOL File]
5731-10-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
235-240 °C | [Boiling point ]
369.4±25.0 °C(Predicted) | [density ]
1.261±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.14±0.10(Predicted) | [color ]
White to Off-White | [CAS DataBase Reference]
5731-10-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [WGK Germany ]
2
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2916399090 |
| Hazard Information | Back Directory | [Uses]
4-(4-Fluorophenyl)benzoic acid (Compoud 6) can bind to Bcl-2 with a KD value of 400 μM. 4-(4-Fluorophenyl)benzoic acid can be used to develope Bcl-2 selective anti-cancer agent[1]. | [References]
[1] Petros AM, et al. Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6587-91. DOI:10.1016/j.bmcl.2010.09.033 |
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