| Identification | Back Directory | [Name]
MT-45 (hydrochloride) | [CAS]
57314-55-3 | [Synonyms]
MT-45 (hydrochloride)
MT-45 dihydrochloride
MT-45 (hydrochloride) (CRM)
MT-45 dihydrochloride(IC-6)
MT-45 dihydrochloride hydrate
MT-45 dihydrochloride solution
1-cyclohexyl-4-(1,2-diphenylethyl)piperazine,hydrochloride
1-cyclohexyl-4-(1,2-diphenylethyl)piperazine,hydrochlorideMT-45
(+-)-1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine dihydrochloride | [Molecular Formula]
C24H34Cl2N2 | [MOL File]
57314-55-3.mol | [Molecular Weight]
421.446 |
| Chemical Properties | Back Directory | [Melting point ]
270-271 °C (decomp) | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) | [form ]
Solid | [color ]
White to Pale Beige | [Major Application]
forensics and toxicology | [InChI]
1S/C24H32N2.2ClH/c1-4-10-21(11-5-1)20-24(22-12-6-2-7-13-22)26-18-16-25(17-19-26)23-14-8-3-9-15-23;;/h1-2,4-7,10-13,23-24H,3,8-9,14-20H2;2*1H | [InChIKey]
PDTBWROWBIVSFO-UHFFFAOYSA-N | [SMILES]
[H]Cl.[H]Cl.C1(C(N2CCN(C3CCCCC3)CC2)CC4=CC=CC=C4)=CC=CC=C1 |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS09 | [Signal word ]
Warning | [Hazard statements ]
H410 | [Precautionary statements ]
P273-P391-P501 | [RIDADR ]
UN1230 - class 3 - PG 2 - Methanol, solution | [WGK Germany ]
WGK 1 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 3
Flam. Liq. 2
STOT SE 1 |
| Hazard Information | Back Directory | [Description]
MT-45 (hydrochloride) (CRM) (Item No. 19737) is a certified reference material categorized as an opioid. It is a novel synthetic opioid that has analgesic activity similar to morphine in animal models. MT-45 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. | [Uses]
MT-45 is a piperazine derivative with potent analgesic activity comparable to morphine. It has been used as a lead compound to develop a large group of potent opioid drugs with agonist or antagonist activities particular to the various opioid receptor subtypes. | [General Description]
MT-45, also known as IC-6, is a piperazone derivative with analgesic activity comparable to morphine. According to a recent report released by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), MT-45 has been associated with deaths in the United States and Sweden, since it emerged on the illicit drug market in 2013. This Certified Spiking Solution? is suitable as starting material for calibrators or controls in MT-45 GC/MS or LC/MS methods for urine drug testing, forensic analysis, or clinical toxicology applications. | [References]
[1] MICHAEL H. BAUMANN . Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace[J]. Neuropharmacology, 2018, 134: Pages 101-107. DOI: 10.1016/j.neuropharm.2017.08.016 |
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