ChemicalBook--->CAS DataBase List--->57576-41-7

57576-41-7

57576-41-7 Structure

57576-41-7 Structure
IdentificationBack Directory
[Name]

Norcepharadione B
[CAS]

57576-41-7
[Synonyms]

Norcepharadione
rcepharadione B
Norcepharadione B
1,2-Dimethoxy-4H-dibenzo[de,g]quinoline-4,5(6H)-dione
4H-Dibenzo[de,g]quinoline-4,5(6H)-dione, 1,2-dimethoxy-
[Molecular Formula]

C18H13NO4
[MDL Number]

MFCD17214804
[MOL File]

57576-41-7.mol
[Molecular Weight]

307.3
Chemical PropertiesBack Directory
[Melting point ]

304-7°C (dec.).
[density ]

1.373±0.06 g/cm3(Predicted)
[pka]

9.90±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

This noraporphindione base occurs, with liriodenine and lysicamine, in the callus tissue of Stephania cephalantha. It forms reddish crystals from EtOH and has been separated from the accompanying bases by column chromatography
[Uses]

Norcepharadione B is an alkaloid that can be isolated from Houttuynia cordata. Norcepharadione B exhibits moderate cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cell line with ED50s of 40, 26.4, 40, 14.2 and 38.2 μg/mL, respectively[1].
[References]

Akasu, Itokawa, Fujita,Phytochem., 14, 1673 (1975)
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