| Identification | More | [Name]
Triphenylethylene | [CAS]
58-72-0 | [Synonyms]
1,1,2-TRIPHENYLETHYLENE
ALPHA-PHENYLSTILBENE
AURORA KA-6581
TRIPHENYLETHYLENE
(1,2-Diphenylvinyl)benzene
1,1’,1’’-(1-ethenyl-2-ylidene)tris-benzen
1,2,2-Triphenylethylene
Benzilidenediphenylmethane
Ethylene, triphenyl-
Triphenylethene
triphenyl-ethylen
Triphenylethylene, 98+%
Benzene, 1,1,1-(1-ethenyl-2-ylidene)tris-
α-phenylstilbene
1,2-Di(phenyl)ethenylbenzene
1,1',1''-(1,1,2-Ethenetriyl)tribenzene
1,1',1''-(1,2,2-Ethenetriyl)tribenzene
1,1,2-Triphenylethene
1,2,2-Triphenylethene | [EINECS(EC#)]
200-395-1 | [Molecular Formula]
C20H16 | [MDL Number]
MFCD00004765 | [Molecular Weight]
256.34 | [MOL File]
58-72-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3
| [RTECS ]
KX4920000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29029080 | [Safety Profile]
Experimental
reproductive effects. Questionable
carcinogen with experimental tumorigenic
data. Human mutation data reported. When
heated to decomposition it emits acrid
smoke and irritating fumes. |
| Hazard Information | Back Directory | [Chemical Properties]
White to slightly beige powder | [Uses]
Triphenylethylene is used in preparation of Esterase activated aggregation-induced luminescent anticancer prodrug. | [Definition]
ChEBI: Triphenylethylene is a stilbenoid. It is the core chemical structure of a number of related anti-estrogen compounds. The triphenylethylene antiestrogens, which include idoxifene, toremifene, chlorotrianisene, raloxifene and tamoxifen, act at the level of the estrogen receptor, triggering inhibition or stimulation of estrogen-dependent gene transcription and cellular physiology. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 78, p. 82, 1956 DOI: 10.1021/ja01582a025
Organic Syntheses, Coll. Vol. 2, p. 606, 1943
Tetrahedron Letters, 14, p. 4193, 1973 |
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