| Identification | More | [Name]
NICOTINOYL-GLYCINE | [CAS]
583-08-4 | [Synonyms]
NICOTINICAMIDO ACETIC ACID
NICOTINOYL-GLYCINE
NICOTINOYL-GLY-OH
NICOTINURIC ACID
NICOTINYLGLYCINE
N-(pyridin-3-ylcarbonyl)glycine
N-NICOTINOYLGLYCINE
N-NicotinuricAcid~99%
N-Nicotinuricacid
Nicotinuric
2-(pyridine-3-carbonylamino)acetic acid
[(Pyridin-3-ylcarbonyl)amino]acetic acid
N-alpha-Nicotinoyl-glycine
Nic-Gly-OH
2-[(3-Pyridylcarbonyl)amino]acetic acid | [EINECS(EC#)]
209-497-0 | [Molecular Formula]
C8H8N2O3 | [MDL Number]
MFCD00023578 | [Molecular Weight]
180.16 | [MOL File]
583-08-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
256-2580C (dec.) | [Boiling point ]
85-90 °C(Press: 12-20 Torr) | [density ]
1.49 g/cm3 | [storage temp. ]
Store at 0-5°C | [solubility ]
Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
3.10±0.10(Predicted) | [color ]
White to Off-White | [Water Solubility ]
Soluble in dimethyl sulfoxide, methanol, water, and 1M NH4OH (50 mg/mL). | [Usage]
Antiproliferative | [InChI]
1S/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12) | [InChIKey]
ZBSGKPYXQINNGF-UHFFFAOYSA-N | [SMILES]
OC(=O)CNC(=O)c1cccnc1 | [CAS DataBase Reference]
583-08-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A Niacin analog for therapeutic use. Antiproliferative. | [Uses]
Antiproliferative | [Uses]
N-Nicotinoylglycine can be used to antiproliferative and as a Niacin analog for therapeutic use.
| [Definition]
ChEBI: An N-acylglycine having nicotinoyl as the acyl substituent. | [Biological Activity]
Nicotinuric acid (NUA) is a metabolite of niacin/vitamin B. Measurement of NUA levels in urine is used to indicate possible elevated nicotinamide adenine dinucleotide (NAD) catabolism. NUA may be used as a reference (standard curve) in the analysis of NAD and NUA catabolism. Nicotinic acid reduces triglycerides and increases high density lipoprotein(HDL) cholesterol. | [IC 50]
Human Endogenous Metabolite |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|