| Identification | Back Directory | [Name]
5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE | [CAS]
583-42-6 | [Synonyms]
SALOR-INT L202959-1EA
5-fluoro-2-mercaptobenzimidazole
2-Mercapto-5-fluorobenzimidazole
5-Fluoro-1H-benzo[d]imidazole-2(3H)
5-Fluoro-1H-benzo[d]imidazole-2(3H)-thione
5-fluoro-1,3-dihydrobenzimidazole-2-thione
5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE
2H-Benzimidazole-2-thione, 5-fluoro-1,3-dihydro-
2H-Benzimidazole-2-thione,5-fluoro-1,3-dihydro-(9CI) | [Molecular Formula]
C7H5FN2S | [MDL Number]
MFCD01029984 | [MOL File]
583-42-6.mol | [Molecular Weight]
168.19 |
| Chemical Properties | Back Directory | [Melting point ]
280 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
261.8±42.0 °C(Predicted) | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
9?+-.0.30(Predicted) | [Appearance]
White to light yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
The reaction was carried out with 4-fluoro-1,2-benzenediamine (10 g, 79.3 mmol) and carbon disulfide (70 ml, 1164 mmol) in methanol (100 ml) with stirring at room temperature for 86 hours and 50 minutes. After completion of the reaction, the reaction mixture was concentrated and the residue was suspended with hexane. The resulting precipitate was collected by filtration and washed with hexane to afford 5-fluoro-1H-benzo[d]imidazole-2(3H)-thione (13.1 g, yield: 98.2%), the product was a brown solid.1H NMR (400 MHz, DMSO-d6) δ ppm: 6.90-6.99 (2H, m), 7.06-7.13 (1H, m). 12.58 (1H, s), 12.61 (1H, s). | [References]
[1] Patent: US2007/10542, 2007, A1. Location in patent: Page/Page column 76 |
|
| Company Name: |
Rhawn Reagent
|
| Tel: |
400-400-1332688 18019345275 |
| Website: |
http://www.rhawn.cn |
| Company Name: |
Cool Pharm, Ltd
|
| Tel: |
021-58581007 18019463053 |
| Website: |
www.coolpharm.com.cn |
|