58754-46-4

Directory

58754-46-4 Structure

Identification	Back Directory
[Name] (E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide
[CAS] 58754-46-4
[Synonyms] S-MPEC iferanserin 2-Propenamide, N-[2-[2-[(2S)-1-methyl-2-piperidinyl]ethyl]phenyl]-3-phenyl- (E)-N-[2-[2-[(2S)-1-methyl-2-piperidyl]ethyl]phenyl]-3-phenyl-prop-2-e namide
[Molecular Formula] C23H28N2O
[MDL Number] MFCD34469254
[MOL File] 58754-46-4.mol
[Molecular Weight] 348.48

Chemical Properties	Back Directory
[storage temp. ] 4°C, away from moisture and light
[form ] Solid
[color ] White to off-white

Hazard Information	Back Directory
[Uses] Iferanserin (S-MPEC) is a selective 5-HT receptor (serotonin receptor) antagonist with an affinity for 5-HT2A receptor. Iferanserin has the potential for internal hemorrhoid disease treatment[1].
[IC 50] 5-HT_2A Receptor
[References] [1] Herold A, et al. Intra-anal Iferanserin 10 mg BID for hemorrhoid disease: a prospective, randomized, double-blind, placebo-controlled trial. Clin Ther. 2012 Feb;34(2):329-40. DOI:10.1016/j.clinthera.2011.12.012

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