| Identification | Back Directory | [Name]
Ofurace | [CAS]
58810-48-3 | [Synonyms]
VAMIN
PATAFOL
OFURACE
re20615
milfuram
ortho20615
chevron20615
Ofurace solution
OFURACE PESTANAL, 100 MG
Ofurace@1000 μg/mL in Acetone
Ofurace @10 μg/mL in Isooctane
2-CHLORO-N-(2,6-DIMETHYLPHENYL)-N-(TETRAHYDRO-2-OXO-3-FURA.
3-(N-Chloracetyl-N-2,6-dimethylphenylamino)-g-butyrolactone
2-chloro-2’,6’-dimethyl-n-(2-oxotetrahydro-3-furyl)-acetanilid
2-chloro-2’,6’-dimethyl-n-(2-oxotetrahydro-3-furyl)acetanilide
2-CHLORO-N-(2,6-DIMETHYLPHENYL)-N-(2-OXOOXOLAN-3-YL)-ETHANAMIDE
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furyl)acetamide
2-chloro-n-(2,6-dimethylphenyl)-n-(tetrahydro-2-oxo-3-furanyl)-acetamid
2-Chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxofuran-3-yl)acetamide
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)-
(+/-)-2-chloro-n-(2,6-dimethylphenyl)-n-(tetrahydro-2-oxo-3-furanyl)-acetamide | [EINECS(EC#)]
261-451-9 | [Molecular Formula]
C14H16ClNO3 | [MDL Number]
MFCD01632753 | [MOL File]
58810-48-3.mol | [Molecular Weight]
281.73 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36 | [Safety Statements ]
36 | [WGK Germany ]
2 | [RTECS ]
AE1300200 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
Ofurace is a systematic fungicide used to control diseases caused by phycomycetes. Ofurace is commonly used in agriculture to control potato late blight. | [Definition]
ChEBI: 2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide is an aromatic amide that is 2,6-dimethylaniline in which the two amino hydrogens are replaced by chloroacetyl and 2-oxotetrahydrofuran-3-yl groups It is an aromatic amide, an organochlorine compound, a butan-4-olide and a tertiary carboxamide. | [Production Methods]
The commercial synthesis of ofurace involves constructing its core structure through acylation and lactone coupling reactions. The process begins with 2,6-dimethylaniline, which undergoes chloroacetylation using chloroacetyl chloride to form 2-chloro-N-(2,6-dimethylphenyl)acetamide. This intermediate is then reacted with tetrahydro-2-oxo-3-furanol, a γ-butyrolactone derivative, under controlled conditions to yield the final compound: Ofurace. The reaction typically takes place in an organic solvent like toluene or acetonitrile, with a base such as triethylamine to facilitate nucleophilic substitution. | [Mechanism of action]
Systemic with curative and protective action. Disrupts fungal nucleic acid synthesis - RNA ploymerase 1. | [Pesticide Type]
Fungicide |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Telephone: |
+86-29-87569266 +86-17392581500 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-220/ |
|