| Identification | Back Directory | [Name]
[LEU5]-ENKEPHALIN | [CAS]
58822-25-6 | [Synonyms]
YGGFL
ENKEPHALIN L
LEU-ENKEPHALIN
Leu-Enkelphalin
Leucyl-enkephalin
[LEU5]-ENKEPHALIN
DYNORPHIN A (1-5)
LEUCINE-ENKEPHALIN
enkephalin,leucine
TYR-GLY-GLY-PHE-LEU
leuthine enkephalin
(5-LEUCIN)ENKEPHALIN*
[5-LEUCINE]ENKEPHALIN
L-TYR-GLY-GLY-PHE-LEU
Tyr-Gly-Gly-Phe-Leu-OH
TYR-GLY-GLY-PHE-LEU H2O
ENKEPHALIN, LEU5-, HUMAN
H-TYR-GLY-GLY-PHE-LEU-OH
ALPHA-NEOENDORPHIN (1-5)
(5-LEUCINE)ENKEPHALIN 96+%
[LEU5]-ENKEPHALIN USP/EP/BP
L-Tyr-Gly-Gly-L-Phe-L-Leu-OH
leucine enkephalin acetate hydrate
Leu-Enkephalin,α-Neoendorphin (1-5)
[5-Leucine]Enkephalin, Enkephalin L
a-Neoendorphin (1-5), Dynorphin A (1-5)
L-Leucine, L-tyrosylglycylglycyl-L-phenylalanyl-
Leu-Enkephalin,α-Neoendorphin (1-5), Dynorphin A (1-5)
LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE)
LEUCINE-ENKEPHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE) H2O
N-[N-[N-(N-L-tyrosylglycyl)glycyl]-L-phenylalanyl]-L-leucine
Leu5]-Enkephalin，Tyr-Gly-Gly-Phe-Leu，YGGFL，ICI-114740，Leu-enkephalin，Leucine enkephalin，Leucyl-enkephalin
[Leu5]-Enkephalin,Tyr-Gly-Gly-Phe-Leu,YGGFL,ICI-114740,Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin?, BR
Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu | [EINECS(EC#)]
261-457-1 | [Molecular Formula]
C28H37N5O7 | [MDL Number]
MFCD00076406 | [MOL File]
58822-25-6.mol | [Molecular Weight]
555.62 |
| Chemical Properties | Back Directory | [Melting point ]
130-133 °C | [alpha ]
+32.3°(c=9,メタノール) | [Boiling point ]
998.8±65.0 °C(Predicted) | [density ]
1.274±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Store in freezer, under -20°C | [solubility ]
≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO | [form ]
Lyophilized powder | [pka]
3.40±0.10(Predicted) | [color ]
White to light yellow | [Water Solubility ]
Soluble in water (1 mg/ml ). | [Sequence]
H-Tyr-Gly-Gly-Phe-Leu-OH | [InChIKey]
URLZCHNOLZSCCA-VABKMULXSA-N | [SMILES]
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N |
| Hazard Information | Back Directory | [Uses]
Endogenous opioid neurotransmitter/neuromodulator that is an agonist at ? and δ opioid receptors, localization in brain parallels the localization of δ receptors. | [Definition]
ChEBI: Leu-enkephalin is a pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. It has a role as a delta-opioid receptor agonist, a mu-opioid receptor agonist, a neurotransmitter, an analgesic, a human metabolite and a rat metabolite. It is functionally related to a L-tyrosine, a glycine, a L-phenylalanine and a L-leucine. It is a tautomer of a Leu-enkephalin zwitterion. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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