| Identification | More | [Name]
N,N-DIETHYLNICOTINAMIDE | [CAS]
59-26-7 | [Synonyms]
ANACARDONE
CORVOTONE
DYNACORYL
EUCORAN
LABOTEST-BB LT00134638
NICAMIDE
NICKETHAMIDE
NICOTINIC ACID DIETHYLAMIDE
NIKETHAMIDE
NIKETHAMIDUM
N,N-DIETHYLNICOTINAMIDE
PYRICARDYL
PYRIDINE-3-CARBOXYLIC ACID DIETHYLAMIDE
3-Pyridinecarboxamide, N,N-diethyl-
Anacordone
Astrocar
beta-Pyrimidum
Camphozone
Canfodiamina
Carbamidal | [EINECS(EC#)]
200-418-5 | [Molecular Formula]
C10H14N2O | [MDL Number]
MFCD00006386 | [Molecular Weight]
178.23 | [MOL File]
59-26-7.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellow liquid | [Melting point ]
23 °C (lit.) | [Boiling point ]
296-300 °C (lit.) | [density ]
1.06 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.524(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
pKa 3.46(H2O,t =20) (Uncertain) | [color ]
Clear colorless to yellow | [Merck ]
6543 | [BRN ]
5743 | [InChI]
InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3 | [InChIKey]
NCYVXEGFNDZQCU-UHFFFAOYSA-N | [SMILES]
C1=NC=CC=C1C(N(CC)CC)=O | [CAS DataBase Reference]
59-26-7(CAS DataBase Reference) | [EPA Substance Registry System]
Nikethamide (59-26-7) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
QS4375000
| [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29333999 | [Safety Profile]
Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. When heated to
decomposition it emits toxic fumes of NOx.
| [Toxicity]
LD50 i.p. in rats: 272 mg/kg (Goldenthal) |
| Hazard Information | Back Directory | [General Description]
Clear light yellow viscous liquid or crystalline solid. Slightly bitter taste followed by a faint sensation of the warmth. | [Reactivity Profile]
NICETHAMID(59-26-7) is incompatible with sodium carbonate solutions which cause precipitation. . | [Air & Water Reactions]
Water soluble. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. | [Fire Hazard]
This chemical is combustible. | [Description]
A further Corydalis alkaloid, coramine has been obtained from C. pseudoadunca
M. Pop. It forms colourless needles from EtOH and is optically active with a
specific rotation of [α]D - 391 ° (c 0.2, MeOH). Both the hydrochloride, m.p.
216-9°C and the hydrobromide, m.p. 223-6°C have been described. | [Chemical Properties]
clear colorless to yellow liquid | [Uses]
analeptic | [Definition]
ChEBI: Nikethamide is a pyridinecarboxamide. It is functionally related to a nicotinamide. | [storage]
Store at -20°C | [References]
Yunusov, Akramov, Yunusov, Dokl. Akad. Nauk. USSR, 162,607 (1965)
Yunusov, Akramov, Yunusov, Khim. Prir. Soedin., 2, 340 (1966)
Ibragimova, Yunusov, Yunusov, ibid, 6,438 (1970)
Yunusov, et al., ibid, 7, 380 (1971) |
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