| Identification | More | [Name]
Butyl chloroformate | [CAS]
592-34-7 | [Synonyms]
BUTYL CHLOROCARBOXYLATE
BUTYL CHLOROFORMATE
CHLOROFORMIC ACID BUTYL ESTER
CHOROFORMIC ACID N-BUTYL ESTER
N-BUTYL CHLOROFORMATE
Butoxycarbonyl chloride
Butyl chloridocarbonate
Butyl chlorocarbonate
carbonochloridicacid,butylester
carbonochloridicacidbutylester
Formic acid, chloro-, butyl ester
N-Butyl Chlorocarbonate
n-Butylchloroformate,97%
n-Buty chloroformate
chloroformic acid n-butyl ester
butyl chloroformate chloroformic acid butyl ester
Chlorocarboxylic acid butyl ester | [EINECS(EC#)]
209-750-5 | [Molecular Formula]
C5H9ClO2 | [MDL Number]
MFCD00000650 | [Molecular Weight]
136.58 | [MOL File]
592-34-7.mol |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS02,GHS05,GHS06 | [Signal word ]
Danger | [Hazard statements ]
H226-H314-H331 | [Precautionary statements ]
P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | [Hazard Codes ]
T | [Risk Statements ]
R10:Flammable.
R23:Toxic by inhalation.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2743 6.1/PG 2
| [WGK Germany ]
1
| [F ]
10-19 | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
6.1 | [PackingGroup ]
I | [HS Code ]
29159020 |
| Hazard Information | Back Directory | [General Description]
A colorless liquid. Flash point near 70°F. Very toxic by inhalation. Denser than water. Used to make other chemicals. | [Reactivity Profile]
N-BUTYL CHLOROFORMATE(592-34-7) is incompatible with bases (including amines), with water, with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. | [Air & Water Reactions]
Highly flammable. Decomposes exothermically in water to give hydrochloric acid and organic acids. | [Health Hazard]
Inhalation of vapor irritates nose and throat and can cause delayed pulmonary edema. Liquid irritates eyes and causes severe skin burns and irreversible skin damage if allowed to remain. Can cause blindness. Ingestion causes burns of mouth and stomach. | [Chemical Properties]
clear liquid | [Uses]
Butyl Chloroformate is a reactant in the preparation of Lapatinib derivatives as HER1/HER2 targeting antitumor drugs. | [Flammability and Explosibility]
Flammable | [Synthesis]
The n-butyl chloroformate was prepared as follows: 1580g of n-butanol (M=74) was preheated to 100°C, added from the upper inlet of the reaction distillation tower using a stratospheric pump, and fully contacted with the phosgene gas (0.5MPa, M=98.9) enter |
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