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59481-27-5

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59481-27-5 Structure

59481-27-5 Structure
IdentificationBack Directory
[Name]

[TYR11 ]-SOMATOSTATIN
[CAS]

59481-27-5
[Synonyms]

tyr(11)-somatostati
somatostatin, Tyr(11)-
Somatostatin (sheep), 11-L-tyrosine- (9CI)
H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys-OH, (Disulfide bond)
[Molecular Formula]

C76H104N18O20S2
[MDL Number]

MFCD00076769
[MOL File]

59481-27-5.mol
[Molecular Weight]

1653.88
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[Sequence]

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys (Disulfide bridge:Cys3-Cys14)
Hazard InformationBack Directory
[Uses]

[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1].
[References]

[1] Vasilaki A, et al. Somatostatin mediates nitric oxide production by activating sst(2) receptors in the rat retina. Neuropharmacology. 2002;43(5):899-909. DOI:10.1016/s0028-3908(02)00181-8
[2] Presky DH, Schonbrunn A. Iodination of [Tyr11]somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells. Mol Pharmacol. 1988;34(5):651-658. PMID:2904115
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