| Identification | Back Directory | [Name]
I-PROPYLISOCYANIDE | [CAS]
598-45-8 | [Synonyms]
2-isocyanopropane
2-Isocyano-propane
I-PROPYLISOCYANIDE
1-Propylisocyanide
ISOPROPYLISOCYANIDE
2-Isonitrilopropane
Isopropyl-isonitrile
isopropylcarbylamine
i-Propylisocyanide,99%
Isopropyl isocyanide 97%
1-Methyl-1-isocyanoethane
I-PROPYLISOCYANIDE,MIN.97%
i-Propylisocyanide, min. 97% | [Molecular Formula]
C4H7N | [MDL Number]
MFCD00015503 | [MOL File]
598-45-8.mol | [Molecular Weight]
69.11 |
| Chemical Properties | Back Directory | [Boiling point ]
75 °C(lit.)
| [density ]
0.733 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.371(lit.)
| [Fp ]
69 °F
| [storage temp. ]
2-8°C | [form ]
liquid | [color ]
colorless | [Specific Gravity]
0.7596 | [Stability:]
store cold |
| Questions And Answer(Q&A) | Back Directory | [Preparation]
To a flask containing 100 ml (0.85 mole) of distilled quinoline is added with stirring 41 gm (0.214 mole) of /7-toluenesulfonyl chloride (see Note), and the solution is warmed to 75°C. Then 18.4 gm (0.212 mole) of isopropylformamide is added and the pressure of the system is reduced to 70 mm Hg. The isopropylisonitrile as it forms distills into a liquid nitrogencooled receiver. (Dry ice is not as effective but may be used.) The product is redistilled to afford 4.2 gm (30%), b.p. 88-89°C (735 mm Hg).
|
| Hazard Information | Back Directory | [Uses]
Isopropyl isocyanide may be used in the preparation of:
- Ugi ligand A2C11I1, which is employed in the solid-phase Ugi synthesis.
- Pentafluorophenyl (PFP) functional monomers, via Passerini reaction.
- Dinuclear copper complex [Cu2(μ-PiPr2bipy)2{μ-CNCH(CH3)2}](PF6)2 [PiPr2bipy = 6-(diisopropylphosphanyl)-2,2′-bipyridine].
- (3E)-(Imino)thiaisoindoline 1,1-dioxide derivative.
- N,N′-diisopropylcarbodiimide (DIC) analog via reaction with propan-2-amine.
- 1-t-butyl-2-isopropyldiaziridinone via reaction with 2-methyl-2-nitrosopropane
- isopropyl isocyanate via reaction with ozone
- 1-phthalimidoazetidines via [1+3]cycloaddition reaction with 1-pththalimidoaziridines
| [General Description]
Isopropyl isocyanide is an alkyl isocyanide. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|