| Identification | Back Directory | [Name]
butyl-delta(9)-tetrahydrocannabinol | [CAS]
60008-00-6 | [Synonyms]
Δ9-THCB
Δ9-THCB (CRM)
butyl-delta(9)-tetrahydrocannabinol
(6aR,10aR)-3-butyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
6H-Dibenzo[b,d]pyran-1-ol, 3-butyl-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-, (6aR-trans)- | [Molecular Formula]
C20H28O2 | [MOL File]
60008-00-6.mol | [Molecular Weight]
300.44 |
| Chemical Properties | Back Directory | [Boiling point ]
375.7±42.0 °C(Predicted) | [density ]
1.024±0.06 g/cm3(Predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
DMF: 50 mg/ml
DMF: PBS (pH 7.2) (1:3): 0.25 mg/ml
DMSO: 60 mg/ml
Ethanol: 35 mg/ml
Methanol: 30 mg/ml | [pka]
9.78±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Δ9-THCB (Δ9-Tetrahydrocannabutol) has a high affinity for human CB1 and CB2 receptors with the Ki values of 15 nM and 51 nM, respectively. Δ9-THCB (Δ9-Tetrahydrocannabutol) has analgesic and anti-inflammatory activities and plays partial agonistic effects on CB1 receptor in mice[1]. | [IC 50]
CB1: 15 nM (Ki); CB2: 51 nM (Ki) | [References]
[1] Linciano P, et al. Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol. J Nat Prod. 2020 Jan 24;83(1):88-98. DOI:10.1021/acs.jnatprod.9b00876 |
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