| Identification | More | [Name]
BOC-7-AMINO-HEPTANOIC ACID | [CAS]
60142-89-4 | [Synonyms]
7-(BOC-AMINO)ENANTHIC ACID
7-(BOC-AMINO)HEPTANOIC ACID
BOC-7-AHP-OH
BOC-7-AMINO-HEPTANOIC ACID
BOC-AHEPT-OH
BOC-NH-(CH2)6-COOH
N-BOC-7-AMINOHEPTANOIC ACID
N-T-BUTOXYCARBONYL-7-AMINOENANTHIC ACID
N-T-BUTOXYCARBONYL-7-AMINOHEPTANOIC ACID
N-TERT-BUTYLOXYCARBONYL-7-AMINOHEPTANOIC ACID
7-Aminoheptanoic acid, N-BOC protected
N-tert-Butoxycarbonyl-7-aminoheptanoic acid
7-(Boc-amino)enanthic acid, 7-(Boc-amino)heptanoic acid, Boc-7-aminoheptanoic acid | [Molecular Formula]
C12H23NO4 | [MDL Number]
MFCD00063356 | [Molecular Weight]
245.32 | [MOL File]
60142-89-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
56-60 °C | [Boiling point ]
393.1±25.0 °C(Predicted) | [density ]
1.050±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
soluble in Methanol | [form ]
powder to crystaline | [pka]
4.77±0.10(Predicted) | [color ]
White to Almost white | [BRN ]
2050867 | [Major Application]
peptide synthesis | [InChI]
1S/C12H23NO4/c1-12(2,3)17-11(16)13-9-7-5-4-6-8-10(14)15/h4-9H2,1-3H3,(H,13,16)(H,14,15) | [InChIKey]
HJENAZQPOGVAEK-UHFFFAOYSA-N | [SMILES]
CC(C)(C)OC(=O)NCCCCCCC(O)=O | [CAS DataBase Reference]
60142-89-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|