ChemicalBook--->CAS DataBase List--->602-41-5

602-41-5

602-41-5 Structure

602-41-5 Structure
IdentificationBack Directory
[Name]

THIOCOLCHICOSIDE
[CAS]

602-41-5
[Synonyms]

r.271
coltramyl
Thiocochicoside
THIOCOLCHICOSIDE
THEOCOLCHICOSIDE
Thiocolchicoside B
2-Glucoside analog
10-thiocolchicoside
10-thio-colchicosid
THIOCOLCHICOSIDE USP/EP/BP
Thiocolchicoside hydrate CRS
Thiocolchicoside EP Impurity F
Thiocolchicine 2-glucoside analog
Thiocolchisine, 2-glucoside analog
2-Demethoxy-2-glucosidoxythiocolchisine
Thiocolchicoside for system suitability CRS
(s)-(methylthio)-9-oxobenzo(a)heptalen-7-yl)
Thiocolchicoside crystallised from ethanol CRS
3,10-DI(DEMETHOXY)-3-GLUCOPYRANOSYLOXY-10-METHYLTHIOCOLCHICINE
n-(3-(beta-d-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-acetamid
(S)-7-Acetylamino-6,7-dihydro-1,2-dimethoxy-3-(β-D-glucopyranosyloxy)-10-(methylthio)benzo[a]heptalen-9(5H)-one
(S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-diMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMid
N-[(S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide
N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-diMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide
N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide
Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-
[EINECS(EC#)]

210-017-7
[Molecular Formula]

C27H33NO10S
[MDL Number]

MFCD07995056
[MOL File]

602-41-5.mol
[Molecular Weight]

563.62
Chemical PropertiesBack Directory
[Melting point ]

190-198?C
[alpha ]

D -609° (water), -240° (ethanol)
[Boiling point ]

929.6±65.0 °C(Predicted)
[density ]

1.2222 (rough estimate)
[refractive index ]

1.6550 (estimate)
[storage temp. ]

Refrigerator
[solubility ]

Methanol (Slightly, Heated), Water (Slightly)
[form ]

Yellow solid.
[pka]

12.74±0.70(Predicted)
[color ]

Light Yellow to Yellow
[Merck ]

14,9324
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)Skull and Crossbones (GHS06)
GHS08,GHS06
[Signal word ]

Danger
[Hazard statements ]

H301-H361-H372-H362
[Precautionary statements ]

P201-P260-P263-P264-P270-P308+P313-P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
[RTECS ]

AC2976015
[HS Code ]

2940.00.6000
[Toxicity]

LD50 intraperitoneal in mouse: 1mg/kg
Hazard InformationBack Directory
[Chemical Properties]

Yellow solid
[Uses]

A GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects.
[Definition]

ChEBI: N-[(7S)-1,2-dimethoxy-10-(methylthio)-9-oxo-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide is a glycoside.
[Biological Activity]

Potent competitive antagonist of GABAAR function. Muscle relaxant. Displays anti-inflammatory and analgesic properties. Shows strong epileptogenic and convulsant activity.
Spectrum DetailBack Directory
[Spectrum Detail]

THIOCOLCHICOSIDE(602-41-5)1HNMR
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