| Identification | Back Directory | [Name]
bursopoietin | [CAS]
60267-34-7 | [Synonyms]
bursopoietin
Bursin【chicken】
L-Lys-L-His-Gly-NH2
Bursin (avian) H-Lys-His-Gly-NH2
Glycinamide, L-lysyl-L-histidyl-
(2S)-2,6-diamino-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]hexanamide | [Molecular Formula]
C14H25N7O3 | [MOL File]
60267-34-7.mol | [Molecular Weight]
339.39 |
| Chemical Properties | Back Directory | [Boiling point ]
872.5±65.0 °C(Predicted) | [density ]
1.289±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.53±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Bursopoietin Cell differentiation agent in extracts of chicken bursa of fabricus. | [Uses]
Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2[1]. | [References]
[1] Wang C, et al. Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol. 2014 Nov-Dec;292(1-2):57-64. DOI:10.1016/j.cellimm.2014.09.003
[2] Audhya T, et al. Tripeptide structure of bursin, a selective B-cell-differentiating hormone of the bursa of fabricius. Science. 1986 Feb 28;231(4741):997-9. DOI:10.1126/science.3484838 |
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