| Identification | Back Directory | [Name]
L-HISTIDINE DIHYDROCHLORIDE | [CAS]
6027-02-7 | [Synonyms]
Nsc 27422
Einecs 227-890-5
L-Histidine dihydrochloride >=99.0% (AT) | [EINECS(EC#)]
227-890-5 | [MDL Number]
MFCD00066569 | [MOL File]
6027-02-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
240-245°C (dec.) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder or crystals | [color ]
white | [Optical Rotation]
[α]20/D +6.5±1°, c =8% in H2O | [Water Solubility ]
H2O: soluble
saline: soluble |
| Hazard Information | Back Directory | [Uses]
L-Histidine dihydrochloride is a histidine derivative[1]. | [Biological Activity]
L-Histidine is a natural proteinogenic α amino acid useful as a cell growth supplement th at support protein and peptide biosynthesis. L-Histidine is studied in a wide range of applications th at involve imidazole chemistry and biochemisty.''L-Histidine is a positively charged imidazole-side chain containing α amino acid. It is metabolized to histamine and is a precursor of the dipeptide carnosine. As one of the 22 proteinogenic amino acids L-His is incorporated into proteins by translation processes in vitro. L-Histidine is an essential amino acid added to cell culture media. | [References]
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368 |
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