| Identification | More | [Name]
N-Cbz-L-histidine | [CAS]
14997-58-1 | [Synonyms]
CBZ-HIS-OH
CBZ-L-HIS-OH
N2-CARBOBENZYLOXY-L-HISTIDINE
N-ALPHA-BENZYLOXYCARBONYL-L-HISTIDINE
NALPHA-CARBOBENZOXY-L-HISTIDINE
N-ALPHA-CARBOBENZYLOXY-L-HISTIDINE
N(ALPHA)-CBZ-L-HISTIDINE
N-ALPHA-Z-L-HISTIDINE
N-CARBOBENZOXY-L-HISTIDINE
N-CBZ-L-HISTIDINE
N-CBZ-L-HISTIDINE-OH
(S)-2-BENZYLOXYCARBONYLAMINO-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID
Z-HIS-OH
Z-HISTIDINE
Z-L-HISTIDINE
Nα-Carbobenzyloxy-L-histidine
Nα-Z-L-Histidine
CBZ-L-Histidine-OH
N(alpha)-Benzyloxycarbonyl-L-histidine~Z-His-OH
N-benzyloxycarbonyl-L-histidine | [EINECS(EC#)]
239-084-0 | [Molecular Formula]
C14H15N3O4 | [MDL Number]
MFCD00065960 | [Molecular Weight]
289.29 | [MOL File]
14997-58-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
168 °C (dec.)(lit.)
| [alpha ]
-24 º (c=1 in 6 M HCl) | [Boiling point ]
616.7±55.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [refractive index ]
-23.5 ° (C=6, 6mol/L HCl) | [storage temp. ]
−20°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder to crystal | [pka]
3.35±0.10(Predicted) | [color ]
White to Almost white | [Optical Rotation]
[α]20/D 24°, c = 1% in 6 M HCl | [Water Solubility ]
almost transparency | [BRN ]
3561682 | [Major Application]
peptide synthesis | [InChI]
1S/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)/t12-/m0/s1 | [InChIKey]
WCOJOHPAKJFUDF-LBPRGKRZSA-N | [SMILES]
OC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OCc2ccccc2 | [CAS DataBase Reference]
14997-58-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29332900 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Nα-Cbz-L-histidine is an N-Cbz-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle. | [reaction suitability]
reaction type: solution phase peptide synthesis |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|