ChemicalBook--->CAS DataBase List--->60561-17-3

60561-17-3

60561-17-3 Structure

60561-17-3 Structure
IdentificationBack Directory
[Name]

SUFENTANIL CITRATE
[CAS]

60561-17-3
[Synonyms]

r33800
Sufenta
Sufentanil Forte
Sufentanyl Citrat
r30730citratesalt
sufentanylcitrate
SUFENTANIL CITRATE
SUFENTANILCITRATE,USP
Sufentanil Citrate solution
Sufentanil Citrate (CII), USP
Sufentanil Citrate CII (25 mg)
Methanol(Test:Sufentanil Citrate, 100 μg/mL as free base)
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-propionanilidcitr
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilidecitrat
n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-n-phenylpropionam
N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide citrate
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide citrate
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl, propanamide 2-Hydroxy-1,2,3-propanetricarboxylate
Propanamide, N-[4-(methoxymethyl)-1-[2- (2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
[EINECS(EC#)]

262-295-4
[Molecular Formula]

C28H38N2O9S
[MDL Number]

MFCD00072116
[MOL File]

60561-17-3.mol
[Molecular Weight]

578.67
Chemical PropertiesBack Directory
[Appearance]

Crystalline Solid
[Melting point ]

96.60C
[Fp ]

9℃
[storage temp. ]

-20°C Freezer
[solubility ]

H2O: soluble1mg/mL, clear
[form ]

powder
[color ]

white to beige
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Chemical Properties]

Crystalline Solid
[Uses]

Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)
[Definition]

ChEBI: Sufentanil citrate is an anilide.
[Brand name]

Sufenta (Akorn).
[General Description]

Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.
[Clinical Use]

Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.
[Veterinary Drugs and Treatments]

An opioid analgesic, sufentanil may be useful as an anesthesia adjunct or as an epidural analgesic. In humans, it has been used as the primary anesthetic in intubated patients with assisted ventilation, and as a post-operative analgesic.
Safety DataBack Directory
[Hazard Codes ]

T+,T,F
[Risk Statements ]

26/27/28-39/23/24/25-23/24/25-11
[Safety Statements ]

26-27-28-36/37/39-45-36/37-16-7
[RIDADR ]

3249
[WGK Germany ]

3
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[HS Code ]

2934910000
[Toxicity]

LD50 intravenous in dog: 14100ug/kg
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