| Identification | Back Directory | [Name]
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98 | [CAS]
60779-49-9 | [Synonyms]
5-Nitro-6-carboxyuracil
5-nitro-2,6-dioxo-3H-pyrimidine-4-carboxylic acid
5-NITROOROTIC ACID POTASSIUM SALT MONOHYDRATE 98%
5-Nitroorotic acid monohydrate potassium salt
5-NITROOROTIC ACID, POTASSIUM SALT MONOHYDRATE, 98
2,6-diketo-5-nitro-3H-pyrimidine-4-carboxylic acid
5-nitro-2,6-dioxo-1,2,3,4-tetrahydropyrimidine-4-carboxylic acid
5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid | [EINECS(EC#)]
262-426-5 | [Molecular Formula]
C5H2KN3O6·H2O | [MDL Number]
MFCD00149396 | [MOL File]
60779-49-9.mol | [Molecular Weight]
257.2 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellow powder | [Synthesis]
Maintaining cooling to below 50°C, 420 ml (7.68 mol) of concentrated sulfuric acid (H2SO4, about 98%) was added to 169 ml (2.56 mol) of 65% nitric acid (HNO3). Then 200 g of whey acid (1.28 mol; 99.64% purity) was added in batches. The reaction mixture wa |
| Questions And Answer | Back Directory | [Application]
In Japan, potassium 5-nitroorotate monohydrate is mainly used as an ingredient in over-the-counter multivitamin medications and as an additive in soft drinks. In Western Europe, it is not only a component of pharmaceutical vitamins but also widely used in cosmetics as a nutritional cosmetic matrix, which can be absorbed by skin cells, promoting cell metabolism and inhibiting skin aging. In the United States, there is considerable research on potassium 5-nitroorotate monohydrate. A series of orotic acid-based drugs, such as nitroorotate and aminoorotate, have been developed both domestically and internationally. Potassium 5-nitroorotate monohydrate possesses an asymmetric spatial structure and various coordination functional groups, enabling it to form a rich variety of coordination compounds with different metal ions. Potassium 5-nitroorotate monohydrate is a key intermediate in the synthesis of dipyridamole, which is a precursor in the synthesis of persantin and aggrenox. |
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Spectrum Chemical Manufacturing Corp.
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