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61230-25-9

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61230-25-9 Structure

61230-25-9 Structure

Identification	Back Directory
[Name] aplasmomycin
[CAS] 61230-25-9
[Synonyms] aplasmomycin
[Molecular Formula] C40H60BNaO14
[MOL File] 61230-25-9.mol
[Molecular Weight] 798.71

Chemical Properties	Back Directory
[Melting point ] 283-285° (dec)
[alpha ] D22 +225° (c = 1.24 in chloroform)

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[Uses] Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo[1].
[Definition] ChEBI: (+)-aplasmomycin is a macrolide antibiotic and a boron oxoanion.
[References] [1] Shimizu Y, et al. Aplasmomycin and boromycin are specific inhibitors of the futalosine pathway. J Antibiot (Tokyo). 2018 Nov;71(11):968-970. DOI:10.1038/s41429-018-0087-2

Safety Data	Back Directory
[Toxicity] LD50 i.p. in mice: 125 mg/kg (Okami)

61230-25-9 suppliers list

Company Name:	Zhejiang Huida Biotech Co., LTD
Tel:	0571-89903022 18679456698
Website:	www.huidacollection.cn

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