| Identification | Back Directory | [Name]
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 | [CAS]
61263-35-2 | [Synonyms]
U 46785
METENPROST
meteneprost
meteneprostum
9-Deoxo-9-Methylene-16,16-diMethyl-PGE2
9-Deoxy-16,16-diMethyl-9-Methylene-PGF2
9-deoxo-16,16-dimethyl-9-methylene-pge2
9-deoxo-16,16-dimethyl-9-methyleneprostaglandine2
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2
9-Deoxo-16,16-dimethyl-9-methyleneprostaglandine E2
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 USP/EP/BP
7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicaci
5-heptenoicacid,7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)
9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID
(5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-diMethyl-9-Methyleneprosta-5,13-dien-1-oic Acid
(5Z,11α,13E,15S)-11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic acid
(5Z,11α,13E,15S)-16,16-Dimethyl-9-methylene-11,15-dihydroxyprosta-5,13-dien-1-oic acid
(5Z,11α,13E,15S)-16,16-Dimethyl-9-methylene-11,15-dihydroxyprosta-5,13-diene-1-oic acid
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, (5Z,11α,13E,15R)- | [Molecular Formula]
C23H38O4 | [MDL Number]
MFCD01723635 | [MOL File]
61263-35-2.mol | [Molecular Weight]
378.55 |
| Chemical Properties | Back Directory | [Boiling point ]
426.61°C (rough estimate) | [density ]
1.0037 (rough estimate) | [refractive index ]
1.4433 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2) | [pka]
4.76±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2; ) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems. | [Uses]
Meteneprost is a potent analog of Prostaglandin E2 (PGE2) (P838610). Meteneprost in combination with various other prostaglandin derivatives is used for medical termination of early pregnancy. | [Definition]
ChEBI: 9-Deoxy-9-methylene-16,16-dimethyl -PGE2 is a long-chain fatty acid. | [storage]
Store at -20°C |
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