| Identification | More | [Name]
Triprolidine hydrochloride | [CAS]
6138-79-0 | [Synonyms]
TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE
pyridine,2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-,monohydrochloride,monohyd
Pyridine,2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride,monohydrate,stereoisomer
rate,stereoisomer
triprolidinesigmareferencestandard
Tripolidine Hydrochloride
TRIPROLIDINE HCL USP
TRIPROLIDINE HCL MONOHYDRATE
trans-TriprolidineHCl
Pyridine, 2-(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl-, monohydrochloride, monohydrate
TRIPROLIDINEHYDROCHLORIDE,USP
2-[(1E)-1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride monohydrate
trans-1-(2-pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene hydrochloride monohydrate
trans-2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride monohydrate
(E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
2-(1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine monohydrochloride
Triprolidine hydrochloride
2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-prop-1-enyl]pyridine
(E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
2-[(E)-1-(4-Methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine hydrate hydrochloride | [EINECS(EC#)]
627-740-2 | [Molecular Formula]
C19H23ClN2 | [MDL Number]
MFCD00150574 | [Molecular Weight]
314.85 | [MOL File]
6138-79-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
115-120°C | [storage temp. ]
2-8°C
| [solubility ]
alcohol: soluble1 in 1.5 of solvent | [form ]
neat | [color ]
White to Off-White | [Stability:]
Stable, but discolours in light. Incompatible with strong oxidizing agents. | [Water Solubility ]
>=10 g/100 mL at 20 ºC | [Usage]
Triprolidine hydrochloride monohydrate is used as bulk pharmaceutical (antihistaminic). Product Data Sheet | [Merck ]
13,9817 | [InChI]
InChI=1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+; | [InChIKey]
WYUYEJNGHIOFOC-NWBUNABESA-N | [SMILES]
C(=C/CN1CCCC1)(\C1=NC=CC=C1)/C1C=CC(C)=CC=1.Cl | [LogP]
4.223 (est) | [CAS DataBase Reference]
6138-79-0(CAS DataBase Reference) | [EPA Substance Registry System]
6138-79-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
UT7658000
| [HS Code ]
2933399090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [General Description]
Odorless white crystalline powder. Bitter taste. | [Reactivity Profile]
TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE(6138-79-0) discolors on exposure to light. | [Air & Water Reactions]
Water soluble. | [Health Hazard]
SYMPTOMS: Symptoms of exposure to this compound may include depression to stimulation of the central nervous system, dry mouth, fixed dilated pupils, flushing, hallucinations, convulsions, urinary retention, cardiac arrhythmias and coma. Other symptoms may include excitability, drowsiness, nervousness, dizziness, high fever and sleeplessness. It can also cause sedation. It may also cause local anesthesia, dryness of the throat and nose and abdominal pain with vomiting or diarrhea. | [Fire Hazard]
Flash point data for this chemical are not available; however, TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE is probably combustible. | [Chemical Properties]
TRIPROLIDINE HYDROCHLORIDE is a white, crystalline powder.
| [Uses]
anticholinergic (opthalmic) | [Uses]
TRIPROLIDINE HYDROCHLORIDE is used as bulk pharmaceutical (antihistaminic). Product Data Sheet
| [Definition]
TRIPROLIDINE HYDROCHLORIDE is a hydrate that is the monohydrate form of triprolidine hydrochloride. A sedating antihistamine, it is used for the symptomatic relief of uticaria, rhinitis, and various pruritic skin disorders.
| [Brand name]
Actidil (GlaxoSmithKline);
Myidyl (USl). | [Biological Activity]
Potent H 1 receptor antagonist. |
|
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|