| Identification | Back Directory | [Name]
(3R)-3β,4α-Bis(3-methoxy-4-hydroxybenzyl)-3-hydroxytetrahydrofuran-2-one | [CAS]
61521-74-2 | [Synonyms]
(+)-Nortrachelogenin, 10 mM in DMSO
(3R)-3β,4α-Bis(3-methoxy-4-hydroxybenzyl)-3-hydroxytetrahydrofuran-2-one
(3R,4R)-3-hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
(3R,4R)-3,4-Bis(4-hydroxy-3-methoxybenzyl)-3-hydroxy-4,5-dihydrofuran-2(3H)-one
(3R,4R)-4,5-Dihydro-3,4-bis(3-methoxy-4-hydroxybenzyl)-3-hydroxyfuran-2(3H)-one
(3R,4R)-4,5-Dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]furan-2(3H)-one
2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-
Phosphoinositide 3-kinase,(+)-Nortrachelogenin,Inhibitor,inhibit,Apoptosis,(+)Nortrachelogenin,PI3K,(+) Nortrachelogenin | [Molecular Formula]
C20H22O7 | [MOL File]
61521-74-2.mol | [Molecular Weight]
374.38 |
| Hazard Information | Back Directory | [Uses]
(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity[1]. | [References]
[1] A Kato,et al. (+)-Nortrachelogenin, A New Pharmacologically Active Lignan From Wikstroemia indica. J Nat Prod. 1979 Mar;42(2):159-162. DOI:10.1021/np50002a004
[2] Huankai Yao, et al. Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway. DOI:10.1007/s11418-020-01447-0 |
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