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61756-22-7

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61756-22-7 Structure

61756-22-7 Structure
IdentificationBack Directory
[Name]

VAL-GLY-SER-GLU
[CAS]

61756-22-7
[Synonyms]

VGSE
ECF-A2
VAL-GLY-SER-GLU
L-VAL-GLY-SER-GLU
Val-Gly-Ser-Glu-OH
H-VAL-GLY-SER-GLU-OH
L-Val-Gly-L-Ser-L-Glu-OH
eosinophilotactic peptide
1-L-Valine eosinophilotactic peptide
L-VALYLGLYCYL-L-SERYL-L-GLUTAMIC ACID)
L-Glutamic acid, L-valylglycyl-L-seryl-
Eosinophil chemotactic factor of anaphylaxis 2
[Molecular Formula]

C15H26N4O8
[MDL Number]

MFCD00076436
[MOL File]

61756-22-7.mol
[Molecular Weight]

390.39
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[Sequence]

H-Val-Gly-Ser-Glu-OH
Hazard InformationBack Directory
[Uses]

Val-Gly-Ser-Glu (NSC 350591) is an ECF-A tetrapeptide. Val-Gly-Ser-Glu dose-dependently increases the number of human eosinophils, but not neutrophils, rosetting with complement-coated sheep erythrocytes (EAC3b)[1].
[References]

[1] Anwar AR, et al. The ECF-A tetrapeptides and histamine selectively enhance human eosinophil complement receptors. Nature. 1977 Oct 6;269(5628):522-4. DOI:10.1038/269522a0
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