| Identification | Back Directory | [Name]
Doxazosin Related Compound F (15 mg) (N,N'-bis(1,4-benzodioxane-2-carbonyl)piperazine) | [CAS]
617677-53-9 | [Synonyms]
Doxazosin Impurity C
Doxazosin EP IMpurity C
Doxazosin Related CoMpound F
Doxazosin Mesilate Impurity C
Doxazosin Mesilate EP Impurity C
Doxazosin USP Related Compound F
1,4-Bis(2,3-dihydro-1,4-benzodioxin
Doxazosin EP Impurity C in salt form
Doxazosin Impurity 3（Doxazosin EP Impurity C）
N,N'-Bis(1,4-benzodioxane-2-carbonyl)piperazine
Doxazosin EP Impurity C/ Doxazosin Related Compund F
piperazine-1,4-diylbis((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone)
Methanone, 1,1'-(1,4-piperazinediyl)bis[1-(2,3-dihydro-1,4-benzodioxin-2-yl)-
Doxazosin Related Compound F (15 mg) (N,N'-bis(1,4-benzodioxane-2-carbonyl)piperazine)
Doxazosin Related Compound F (N,N''-bis(1,4-benzodioxane-2-carbonyl)piperazine) (1225485)
[4-(2,3-dihydro-1,4-benzodioxine-3-carbonyl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone | [Molecular Formula]
C22H22N2O6 | [MDL Number]
MFCD03900355 | [MOL File]
617677-53-9.mol | [Molecular Weight]
410.42 |
| Chemical Properties | Back Directory | [Melting point ]
> 150°C (Dec) | [Boiling point ]
646.9±55.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Dichloromethane (Slightly) | [form ]
Solid | [pka]
-1.53±0.70(Predicted) | [color ]
White to Pale Beige | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1S/C22H22N2O6/c25-21(19-13-27-15-5-1-3-7-17(15)29-19)23-9-11-24(12-10-23)22(26)20-14-28-16-6-2-4-8-18(16)30-20/h1-8,19-20H,9-14H2 | [InChIKey]
RYWJYOGVNZEBKW-UHFFFAOYSA-N | [SMILES]
N1(C(C2COC3=CC=CC=C3O2)=O)CCN(C(C2COC3=CC=CC=C3O2)=O)CC1 |
| Hazard Information | Back Directory | [Uses]
N,N’-Bis(1,4-benzodioxane-2-carbonyl)piperazine (Doxazosin EP Impurity C) is an impurity in the synthesis of Doxazosin (D537500), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate. |
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