ChemicalBook--->CAS DataBase List--->70918-74-0

70918-74-0

70918-74-0 Structure

70918-74-0 Structure
IdentificationMore
[Name]

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
[CAS]

70918-74-0
[Synonyms]

1-(1,4-BENZODIOXANE-2-CARBONYL)PIPERAZINE HYDROCHLORIDE
1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
1,4-BENZODIOXAN-2-CARBONYL PIPERAZINE HCL
(2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)-PIPERAZIN-1-YL-METHANONE HYDROCHLORIDE
(2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)PIPERAZINE-1-YL-METHANONE HYDROCHLORIDE
N-(1,4-BENZODIOXAN-2-CARBONYL)-PIPERAZINE HCL
N-(1,4-BENZODIOXAN-2-CARBONYL)PIPERAZINE HYDROCHLORIDE
N-[(1,4-BENZODIOXANE-2-YL)CARBONYL]PIPERAZINE HCL
N-[(1,4-BENZODIOXANE-2-YL)CARBOXYL] PIPERAZINE HYDROCHLORIDE
N-(2,3-DIHYDRO-1,4-BENZODIOXANE-2-CARBONYL)PIPERAZINE HYDROCHLORIDE
TIMTEC-BB SBB003004
N-[(1,4-benzodioxane-2-yl)carbonyl]piperazine hydrochloride
1-[(1,4-Benzodioxane-2-Yl)Carboxyl]Piperazine Hydrochloride
(2,3-Dihydrobenzo[1.4]dioxin-2-yl)piperazine-1-yl-methanone
N-(2,3-Dihydro-1,4-Benzodioxane-2-Carbonyl)Piperazine HCl
N-(1,4-Benzodioxan-2-carbonyl)piperazine hydrochloride 98%
(2,3-Dihydro-benzo[1,4]dioxin-2-yl)piperazine-
N-(1,4-BENZODIOXANE-2-CARBONYL) PIPERAZINE DIHYDRO
1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)PIPERAZINE HCL
1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride
[EINECS(EC#)]

415-660-9
[Molecular Formula]

C13H17ClN2O3
[MDL Number]

MFCD00729051
[Molecular Weight]

284.74
[MOL File]

70918-74-0.mol
Chemical PropertiesBack Directory
[Melting point ]

105-108°C
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

powder to crystal
[color ]

White to Almost white
[Stability:]

Hygroscopic
[Major Application]

pharmaceutical
[InChI]

InChI=1S/C13H16N2O3.ClH/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12;/h1-4,12,14H,5-9H2;1H
[InChIKey]

TUKBWYXLYINULI-UHFFFAOYSA-N
[SMILES]

C12=CC=CC=C1OCC(C(=O)N1CCNCC1)O2.Cl
[CAS DataBase Reference]

70918-74-0(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H301+H311+H331-H373-H411
[Precautionary statements ]

P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314
[Hazard Codes ]

T;N,Xi,N,T
[Risk Statements ]

R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S53:Avoid exposure-obtain special instruction before use .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
[RIDADR ]

UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all
[WGK Germany ]

WGK 3
[Hazard Note ]

Irritant
[REACH Registrations]

Inactive
[HazardClass ]

6.1
[PackingGroup ]

III
[HS Code ]

2934990002
[Storage Class]

6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 2
STOT RE 2 Oral
Hazard InformationBack Directory
[Uses]

1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
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