| Identification | Back Directory | [Name]
4-HYDROXY MEPHENYTOIN | [CAS]
61837-65-8 | [Synonyms]
4-HYDROXY MEPHENYTOIN
4'-Hydroxymephenitoyn
(+/-) -HYDROXYMEPHENYTOIN
(+/-)-4-HYDROXYMEPHENYTOIN
4-HydroxyMephenytoin >=98% (HPLC)
5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl-
5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin
(+/-)-5-ETHYL-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN
(+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLHYDANTOIN
4-Hydroxy-5-ethyl-3-methyl-5-phenylimidazolidin-2-one
5-Ethyl-3-methyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione
5-ethyl-5-(4-hydroxyphenyl)-3-MethyliMidazolidine-2,4-dione
5-(p-Hydroxyphenyl)-3-methyl-5-ethyl-imidazolidine-2,4-dione
(+/-)-5-ETHYL-5-(4-HYDROXYPHENYL)-3-METHYLIMIDIDAZOLIDINE-2,4-DIONE
(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione | [Molecular Formula]
C12H14N2O3 | [MDL Number]
MFCD00142316 | [MOL File]
61837-65-8.mol | [Molecular Weight]
234.25 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
153-154 °C
| [density ]
1.249±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO: >5mg/mL | [form ]
Solid | [pka]
8.31±0.70(Predicted) | [color ]
white
| [InChI]
1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17) | [InChIKey]
OQPLORUDZLXXPD-UHFFFAOYSA-N | [SMILES]
CCC1(NC(=O)N(C)C1=O)c2ccc(O)cc2 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
CYP2C19 metabolite of Mephenytoin | [Uses]
Pharmacological activity investigating:• ;The drug effects on metabolization1• ;In vitro cytochrome P450 activity in microsomes2Analyte for electron-capture gas chromatography procedures3 | [Definition]
ChEBI: Hydroxymephenytoin is an imidazolidine-2,4-dione. | [General Description]
CYP2C19 metabolite of mephenytoin. | [Biochem/physiol Actions]
4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized. |
|
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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