Identification | Back Directory | [Synonyms]
zami420 Triletide AC-PHE-PHE-HIS-OME TRIPEPTIDE ZAMI 420 ACETYL-L-PHENYLALANYL-L-PHENYALANYL-L-HISTIDINE METHYL ESTER N-Acetyl-L-phenylalanyl-L-phenylalanyl-L-histidine methyl ester L-Histidine, N-acetyl-L-phenylalanyl-L-phenylalanyl-, methyl ester | [MDL Number]
MFCD00153590 |
Hazard Information | Back Directory | [Uses]
Triletide is a thromboxane A2 antagonist with good oral absorption activity. The biotransformation of Triletide mainly includes the formation of demethyl, deacetyl, demethyl-deacetyl and hydroxy derivatives. The distribution half-life of Triletide is about 1 hour, and the elimination half-life is about 5 hours[1]. | [References]
[1] Preliminary human pharmacokinetics of triletide PMID:4059299 |
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