| Identification | More | [Name]
CBZ-BETA-AMINO-D-ALANINE | [CAS]
62234-37-1 | [Synonyms]
CBZ-BETA-AMINO-D-ALANINE
N-ALPHA-BENZYLOXYCARBONYL-D-2,3-DIAMINOPROPIONIC ACID
N-ALPHA-CARBOBENZOXY-D-ALPHA,BETA-DIAMINOPROPIONIC ACID
N-ALPHA-Z-D-2,3-DIAMINOPROPIONIC ACID
N-CBZ-L-2,3-DIAMINOPROPIONIC ACID
Z-D-2,3-DIAMINOPROPIONIC ACID
Z-D-ALPHA,BETA-DIAMINOPROPIONIC ACID
Z-D-DAP-OH
Nα-Z-D-2,3-Diaminopropionic acid
Z-D-Dpr-OH
N-.ALPHA.-CBZ-D-2,3-DIAMINOPROPIONIC ACID
Z-D-Dpr-OH, Nα-Z-D-2,3-Diaminopropionic acid | [Molecular Formula]
C11H14N2O4 | [MDL Number]
MFCD02683222 | [Molecular Weight]
238.24 | [MOL File]
62234-37-1.mol |
| Questions And Answer | Back Directory | [Synthesis]
CBZ-BETA-AMINO-D-ALANINE has been reported in the literature to be prepared by reacting N-benzyloxycarbonyl-D-asparagine with iodoacetic acid phenyl diacetate. 
At ambient temperature, N-benzyloxycarbonyl-D-asparagine (5.0 g) was added to a stirred solution of iodoacetic acid phenyl diacetate (7.26 g) in a mixture of ethyl acetate (44 ml), acetonitrile (44 ml), and water (22 ml). After stirring for 3 hours, the reaction mixture was cooled to 50°C and then stirred for 2 hours. The insoluble matter was collected by filtration, washed with ethyl acetate, and dried under reduced pressure to give N(α)-ZD-2,3-diaminopropionic acid, a white solid, with a yield of 4.15 g. IR (KBr) : 3303.5, 3027.7, 2948.6, 1693.2, 1656.5, 1623.8, 1592.9, 1542.8 cm-1 .1HNMR (D2O-TFA, δ ) : 3.35 (1H, dd, J=13.4 and 8.7Hz), 3.57 (1H, dd, J=13.4 and 5.3Hz), 4.57 (1H, dd, J=8.7 and 5.3Hz), 5.16 (2H, s), 7.43 (5H, s) MASS (m/z) : 239 (M+H)+ mp : 238°C (dec.) [α ]D31 : 8.6° (c=1.0, 1N NaOH aq.) |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
~240 °C (dec.) | [Boiling point ]
463.8±45.0 °C(Predicted) | [density ]
1.303±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT. | [pka]
2.86±0.16(Predicted) | [Optical Rotation]
[α]20/D +39.5±1°, c = 1% in 1 M HCl | [BRN ]
1993024 | [CAS DataBase Reference]
62234-37-1(CAS DataBase Reference) |
|
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|