Identification | Back Directory | [Name]
SALUSIN-BETA (HUMAN) | [CAS]
624735-23-5 | [Synonyms]
Salusin- β SALUSIN-BETA SALUSIN –ALFA Salusin-b (huMan) AIFIFIRWLLKLGHHGRAPP SALUSIN-BETA (HUMAN) ALA-ILE-PHE-ILE-PHE-ARG-TRP-LEU-LEU-LYS-LEU-GLY-HIS-HIS-GLY-ARG-ALA-PRO-PRO ALA-ILE-PHE-ILE-PHE-ILE-ARG-TRP-LEU-LEU-LYS-LEU-GLY-HIS-HIS-GLY-ARG-ALA-PRO-PRO H-ALA-ILE-PHE-ILE-PHE-ILE-ARG-TRP-LEU-LEU-LYS-LEU-GLY-HIS-HIS-GLY-ARG-ALA-PRO-PRO-OH SER-GLY-ALA-LEU-PRO-PRO-ALA-PRO-ALA-ALA-PRO-ARG-PRO-ALA-LEU-ARG-ALA-GLN-ARG-ALA-GLY-PRO-ALA-GLY-PRO-GLY-ALA-LYS-NH2 L-Alanyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-tryptophyl-L-leucyl-L-leucyl-L-lysyl-L-leucylglycyl-L-histidyl-L-histidylglycyl-L-arginyl-L-alanyl-L-prolyl-L-proline L-Proline, L-alanyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-tryptophyl-L-leucyl-L-leucyl-L-lysyl-L-leucylglycyl-L-histidyl-L-histidylglycyl-L-arginyl-L-alanyl-L-prolyl- | [Molecular Formula]
C115H176N32O21 | [MDL Number]
MFCD08460349 | [MOL File]
624735-23-5.mol | [Molecular Weight]
2342.83 |
Hazard Information | Back Directory | [Uses]
Salusin-β is an endogenous bioactive peptide with significant hemodynamic and mitogenic activity. Salusin-β can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate. In addition, Salusin-β can stimulate the release of arginine vasopressin from the pituitary gland in rats. This makes Salusin-β have important application potential in cardiovascular disease research[1]. | [References]
[1] Shichiri, et al. "Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities." Nature medicine 9.9 (2003): 1166-1172. DOI:10.1038/nm913 |
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