| Identification | Back Directory | [Name]
SALUSIN-ALPHA (HUMAN) | [CAS]
624735-22-4 | [Synonyms]
SALUSIN-ALPHA
Salusin α(human)
Salusin-a (huMan)
SALUSIN-ALPHA (HUMAN)
SGALPPAPAAPRPALRAQRAGPAGPGAK-NH2
SER-GLY-ALA-LEU-PRO-PRO-ALA-PRO-ALA-ALA-PRO-ARG-PRO-ALA-LEU-ARG-ALA-GLN-ARG-ALA-GLY-PRO-ALA-GLY-PRO-GLY-ALA-LYS-NH2
H-SER-GLY-ALA-LEU-PRO-PRO-ALA-PRO-ALA-ALA-PRO-ARG-PRO-ALA-LEU-ARG-ALA-GLN-ARG-ALA-GLY-PRO-ALA-GLY-PRO-GLY-ALA-LYS-NH2
L-Lysinamide, L-serylglycyl-L-alanyl-L-leucyl-L-prolyl-L-prolyl-L-alanyl-L-prolyl-L-alanyl-L-alanyl-L-prolyl-L-arginyl-L-prolyl-L-alanyl-L-leucyl-L-arginyl-L-alanyl-L-glutaminyl-L-arginyl-L-alanylglycyl-L-prolyl-L-alanylglycyl-L-prolylglycyl-L-alanyl- | [Molecular Formula]
C114H192N40O30 | [MDL Number]
MFCD06660067 | [MOL File]
624735-22-4.mol | [Molecular Weight]
2602.99 |
| Hazard Information | Back Directory | [Uses]
Salusin-α is an endogenous bioactive peptide with hemodynamic and cell proliferation activities. Salusin-α can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate, but its effect is weaker than that of Salusin-β (HY-P10617). Salusin-α has potential application value in cardiovascular disease research[1]. | [References]
[1] Shichiri, et al. "Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities." Nature medicine 9.9 (2003): 1166-1172. DOI:10.1038/nm913 |
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