| Identification | Back Directory | [Name]
4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one | [CAS]
62499-71-2 | [Synonyms]
Isodihydrofutoquinol B
4-[2-(1,3-Benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-2,5-cyclohexadien-1-one
2,5-Cyclohexadien-1-one, 4-[(1R)-2-(1,3-benzodioxol-5-yl)-1-methylethyl]-4,5-dimethoxy-2-(2-propen-1-yl)-, (4S)- | [Molecular Formula]
C21H24O5 | [MOL File]
62499-71-2.mol | [Molecular Weight]
356.41 |
| Hazard Information | Back Directory | [Uses]
Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E50 values of 3.06-29.3μM[1]. | [References]
[1] Chen H, et al. Neolignans and amide alkaloids from the stems of Piper kadsura and their neuroprotective activity. Phytochemistry. 2022 Nov;203:113336. DOI:10.1016/j.phytochem.2022.113336
[2] Prasad A K, et al. Lignans and neolignans from stems and fruits of Piper wightii[J]. Tetrahedron, 1994, 50(7): 2231-2240. |
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