| Identification | More | [Name]
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE | [CAS]
6270-07-1 | [Synonyms]
N-[2-(4-NITROPHENYL)ETHYL]ACETAMIDE
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE
N-ACETYL-4-NITROPHENETHYLAMINE
n-(2-(p-nitrophenyl)ethyl)acetamide
n-[2-(4-nitrophenyl)ethyl]-acetamid
Acetylnitrophenylethylamine
N-(4-NITROPHENETHYL)ACETAMIDE
N-(4-NITROPHENYLETHYL)ACETAMID | [Molecular Formula]
C10H12N2O3 | [MDL Number]
MFCD00024805 | [Molecular Weight]
208.21 | [MOL File]
6270-07-1.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Pale yellow powder | [Uses]
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
450Kg of concentrated sulfuric acid was added to the reactor, the temperature of the reaction solution was room temperature, the reaction solution containing the intermediate 1 was slowly added dropwise, and after sufficient stirring, 75 kg of 70% nitric acid was slowly added. After stirring until completion of the reaction, 800kg of crushed ice was added to the reaction solution and stirred constantly , Finally, pH was adjusted to 7~8 with ammonia solution to give crude product after filtration, crude product was recrystallized from methyl ethyl ketone to give 140 Kg of Intermediate 2, with a yield of 81.5%. |
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