| Identification | Back Directory | [Name]
2-amino-4-phosphonobutyric acid | [CAS]
6323-99-5 | [Synonyms]
2-Amino-4-phosphonobutanoic acid
Butanoic acid, 2-amino-4-phosphono-
DL-2-Amino-4-phosphonobutyric Acid, 98.0+ % (HPLC) | [Molecular Formula]
C4H10NO5P | [MDL Number]
MFCD00013999 | [MOL File]
6323-99-5.mol | [Molecular Weight]
183.1 |
| Chemical Properties | Back Directory | [Melting point ]
229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5)) | [Boiling point ]
491.7±55.0 °C(Predicted) | [density ]
1.628±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM) | [form ]
White solid. | [pka]
2.19±0.10(Predicted) | [Water Solubility ]
Soluble to 50 mM in water |
| Hazard Information | Back Directory | [Description]
DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices. | [Uses]
DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina. Improves learning and memory processes in passive and active avoidance situations in rats. | [storage]
Store at RT |
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